Research: Controlling MS genes

Alcina A et al. Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis. J Med G...

Pharmacogenomics of interferon responses

Kulakova et al. Allelic combinations of immune-response genes as possible composite markers of IFN-β efficacy in multiple sclerosis patients...

Rebound on withdrawal of natalizumab and fingolimod

# MSBlog : MSers on more active maintenance treatments are at risk of rebound in disease activity when the drugs are withdrawn and the barba...

Research Day Advent Calendar 1

Today MouseDoc does Prof B.  The likeness is almost uncanny!   Shame about the ummy video Some of you think he is Superman, well only his ...

Unrelated Blogger Comments

Sometimes you wa n t to say something that is unrelated to the threads. This is a spot for You. Previous comments can be got at on the pos...

Hit hard and early!

The slides from my talk in Marbella; you can download them from my slideshare site!  "The main messages in the talk are: 1. We must ado...

Research: markers of severity?

Epub : Lindén et al. Multiple sclerosis risk genotypes correlate with an elevated cerebrospinal fluid level of the suggested prognostic ma...

Practising to be Santa

You like to comment on Prof Gs jollies, so next week and a bit involves flying back and forth to USA and back to UK for a day meeting and t...

Research Day Advent Calender Starting Soon

Following on from lasts years bit of December fun, it is again time for the House of Mouse Christmas Advent Calender.  Last year my outfits...

The BigPharma Alternative

#MSBlog : Is there an alternative to BigPharma? Help make it happen! Is there an alternative to Big Pharma for developing new drugs for MS? ...

All Party Parlimentary Group for Multiple Sclerosis

Minster for Health; Jeremy Hunt (Constiuency-South West Surrey)  Did you know that there is the All-Party Parliamentary Group for Multiple ...

Research: Blood Products triggers Microglia to cause Damage

Davalos D et al. Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation...

Research: Measuring Fatigue

Epub : Yu et al.  A wireless body measurement system to study fatigue in multiple sclerosis. Physiol Meas. 2012;33(12):2033-2048.  Fatigue ...

ECF Meeting Marbella: natural history and gut microbiota

#MSBlog : Hit hard and early! "I will be speaking at the European Charcot Foundation meeting in Marbella later this week (see programme...

Education: progressive MSers in the same boat.

There has been some questions about the course of MS and whether the cause of relapsing MS and progressive MS are dependent or independent. ...

Research: cognitive impairment in young MSers

Epub :  Julianet al. Cognitive Impairment Occurs in Children and Adolescents With Multiple Sclerosis: Results From a United States Network....

Research: Course in Young MSers

Harding KE, Liang K, Cossburn MD, Ingram G, Hirst CL, Pickersgill TP, Te Water Naude J, Wardle M, Ben-Shlomo Y, Robertson NP. Long-term outc...

Research: JC virus responses & natalizumab

#MSBlog: Steroids reduce the immune response to the JC virus that causes PML. Therefore steroids should only be used to treat not prevent IR...

The Elephant in the Room.

"Elephant in the room" This is an English metaphorical idiom for an obvious truth that is either being ignored or going unadd...

Drug policy for an aging population

#MSBlog : "Most trials exclude older MSers; apologies I don't make the rules!" "At the end of the ' Living with MS ...

Cognitive fatigue and exercise

#MSBlog: "Cognitive and physical exercise, or loading, exacerbates cognitive fatigue." Epub :  Claros-Salinas et al. Induction of ...